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Anti -TLE 1 Rabbit pAb

货号:GB11897

品牌:Servicebio

价格:¥650

规格: 100 μl

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Product Information

 

 

Description

TLE 1 rabbit polyclonal

Protein full name

Transducin-like enhancer protein 1

Synonyms

Tle1, TLE1, ESG, ESG1, GRG1, transducin like enhancer of split 1, TLE family member 1, transcriptional corepressor

Immunogen

Recombinant protein corresponding to Mouse TLE 1

Isotype

IgG

Purity

Affinity purification

Subcellular location
 
Nucleus
 
Uniprot ID

Q9NR28, Q9JIQ3

 


 

Applications

 

 

Applications

IHC

IF
 
Species

Mouse, Rat

Mouse, Rat
Dilution

1: 1000-1: 2000

1: 500-1: 1000
 
Positive tissue lung, brain lung, brain
 

 


 

Background

 

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. 

            


 

Images

 

 

Immunohistochemistry analysis of paraffin-embedded mouse lung using
TLE 1 (GB11897) at dilution of 1: 2000

   

Immunohistochemistry analysis of paraffin-embedded mouse brain using
TLE 1 (GB11897) at dilution of 1: 2000
 
   

Immunohistochemistry analysis of paraffin-embedded rat brain using
TLE 1 (GB11897) at dilution of 1: 2000
 

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

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